Freelite Serum Free Light Chain Assays
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Latest News Headlines
- Automated Analyser for Serum/Plasma Protein Analysis01 July 2009
- Binding Site sponsors Free Light Chain Disease workshop at Euromedlab 200909 April 2009
- Further study indicates only serum measurements needed for MM diagnosis or exclusion10 February 2009
- Publication of largest Light Chain Escape – Multiple Myeloma study to date03 February 2009
- Serum free light chain assays now on Roche cobas 600027 January 2009
- New International guidelines clarify recommendations for using serum free light chain analysis08 December 2008
- New paper suggests sFLC assays aid assessment of acute renal failure01 December 2008
- NEW 5th edition Serum Free Light Chain Analysis (plus Hevylite)17 November 2008
Freelite is a major breakthrough for the detection and monitoring of Multiple Myeloma (MM) and other B-cell dyscrasia. There is now significant clinical evidence indicating the benefit of serum free light chain assays in initial screening for monoclonal gammopathies, identifying AL amyloidosis and Nonsecretory MM patients missed by conventional electrophoretic methods, as a prognostic indicator for progression in myeloma*, for risk stratification of MGUS patients* and rapid evaluation of treatment efficacy.
Freelite assays were developed by Binding Site to measure free lambda and free kappa immunoglobulin light chains. Our expertise in the manufacture of antibodies has enabled us to provide a quantifiable, highly specific, automatable free light chain assay for serum.
Review the clinical evidence for the utility of Freelite in detecting and monitoring plasma cell disorders and compare the results from laboratory protocols with and without Freelite.
* In the USA diagnostic use of this product is restricted to those stated in the product insert
Latest News 01 July 2009
Automated Analyser for Serum/Plasma Protein Analysis
The SPAPLUS™ is a dedicated serum and plasma protein analyser supplied by Binding Site. This compact, easy to use turbidimetric analyser provides a level of functionality usually seen only in larger analysers. The combination of an air mixing system, dual compartment reaction cuvettes and a hot water wash make the SPAPLUS ideal for Binding Site's latex assays. Other features include an automatic antigen excess check, automated rerun and autodilution capability plus Windows®-based software and bidirectional interface.
SPAPLUS assays currently include:
- Freelite™ serum free light chain assays
- IgG subclasses (IgG1 - IgG4)
- IgG, IgA, IgM
- Cystatin C
- ß2 Microglobulin
- Tetanus toxoid
Assays in development include Hevylite™, IgA subclasses and IgD.
SPAPLUS is currently available in UK, USA, Canada, France, Germany, Austria and Spain. In other countries please check with your local Binding Site supplier. More


