Assays
Freelite comprises two new immunodiagnostic assays for accurate and rapid quantification of free kappa and free lambda light chain concentrations in serum.
Affinity purified polyclonal antibodies, reacting specifically with the free forms of kappa and lambda light chain, are precoated onto latex particles. These latex reagents are used to produce nephelometric and turbidimetric kits that are specific for free light chains. The greater sensitivity of these assays means that for the first time in routine practice, serum free light chains can be detected and quantitated down to normal levels. Assays are available on a wide range of automated platforms, ensuring accuracy and reduced hands on time.
Freelite Technical Bulletin No.F001.01 4th September 2006
As the number of laboratories and physicians using Freelite serum free light chain assays continues to grow, we will be sharing new information on the use of these assays via Technical Bulletins. Click here to view bulletin No.F001.01.
Freelite Kits Available
| Analyser | Description | Pack | Code |
|---|---|---|---|
| Dade Behring BN™II |
Freelite Kappa Kit | 2 X 50 test | LK016.T |
| Freelite Lambda Kit | 2 X 50 test | LK018.T | |
| Freelite Kappa Bulk Kit | 20 X 50 test | LK016.10T | |
| Freelite Lambda Bulk Kit | 20 X 50 test | LK018.10T | |
| Dade Behring BN Prospec® |
Freelite Kappa Kit* | 2 X 50 test | LK016.P |
| Freelite Lambda Kit* | 2 X 50 test | LK018.P | |
| Beckman Coulter IMMAGE® |
Freelite Kappa Kit | 2 X 50 test | LK016.IM |
| Freelite Lambda Kit | 2 X 50 test | LK018.IM | |
| Roche Hitachi 911/912/917/P Module |
Freelite Kappa Kit | 2 X 50 test | LK016.H |
| Freelite Lambda Kit | 2 X 50 test | LK018.H | |
| Freelite Kappa Bulk Kit | 20 X 50 test | LK016.10H | |
| Freelite Lambda Bulk Kit | 20 X 50 test | LK018.10H | |
| Roche COBAS Integra® 400 plus |
Freelite Kappa Kit | 1 X 100 test | LK016.RI |
| Freelite Lambda Kit | 1 X 100 test | LK018.RI | |
| Olympus AU400/640/2700/5400 |
Freelite Kappa Kit | 2 X 50 test | LK016.AU |
| Freelite Lambda Kit | 2 X 50 test | LK018.AU | |
| Bayer ADVIA® 1650/2400 |
Freelite Kappa Kit | 2 X 50 test | LK016.B |
| Freelite Lambda Kit | 2 X 50 test | LK018.B | |
| Binding Site SPAPLUS™ |
Freelite Kappa Kit** | 1 X 100 test | LK016.S |
| Freelite Lambda Kit** | 1 X 100 test | LK018.S | |
| Radim Delta™ | Freelite Kappa Kit* | 2 X 50 test | LK016.DL |
| Freelite Lambda Kit* | 2 X 50 test | LK018.DL |
*Please enquire regarding the current FDA status.
**These kits are only available in the USA and Canada and as part of a SPAPLUS reagent rental package.
Protocols for other instruments are being developed so please contact us for the latest information.
Kit Contents
Each comprehensive kit provides components required to perform 100 free kappa or 100 free lambda assays. Liquid stable reagents are provided as 2 x 50 tests or 1 x 100 tests, as indicated. Bulk kits contain reagents for 1000 tests.
- Calibrators
- Controls (1 x high and 1 x low)
- Liquid latex reagent
The liquid latex, calibrator and controls can be stored for up to 3 months at 2-8ºC after opening.
Kits are FDA cleared for in vitro diagnostic use to aid in the diagnosis and monitoring of Multiple Myeloma, Lymphocytic neoplasms, Waldenström's macroglobulinaemia, AL amyloidosis, Light Chain Deposition Disease and connective tissue diseases such as Systemic Lupus Erythematosus.
Freelite is CE marked for many European countries, please contact us for the latest information.
Please contact your local supplier to place an order or for price information.
BN™II and BN ProSpec® are trademarks of Siemens Healthcare Diagnostics Inc.
IMMAGE® is a registered trademark of Beckman Instruments Inc, Brea, CA, USA.
COBAS Integra® is a registered trademark of F. Hoffman-La Roche Ltd, Basel, Switzerland.
Olympus and AU are registered trademarks of Olympus Corporation,Tokyo, Japan.
SPAPLUS is a trademark of The Binding Site, Birmingham, UK.
ADVIA® is a registered trademark of Siemens Healthcare Diagnostics Inc.
DeltaTM is a trademark of SEAC S.r.l., Calenzano, Florence, Italy.
