Eliminate the need for urine Bence Jones Protein testing

Screening FlyerTwo recently published studies indicate clearly that if you replace urine Bence Jones Protein tests with serum assays including Freelite free light chains, during the initial investigation for Multiple Myeloma, all patients requiring medical intervention are identified.


"Urine tests are no longer necessary as part of the screening algorithm for identifying monoclonal gammopathies...
"1

"..no significant pathology would have been missed by replacing BJP with serum FLCs."2

Remove the inconvenience and improve your detection rate

Increase your detection rate by including Freelite in your investigation protocol. Freelite enables sensitive quantification of serum free light chains for diagnosis without the added complications and difficulties of urine collection and testing.2

The superior sensitivity of Freelite allows measurement down to normal levels allowing more accurate detection of Multiple Myeloma, Light Chain Multiple Myeloma, Nonsecretory Multiple Myeloma, AL amyloidosis and some other B cell dyscrasia.3

PatientReduce the impact of patient compliance

Reports of only 40% patient compliance in producing 24-hour urines have been cited.2 Lack of compliance can be due to many factors including renal impairment, embarrassment and inconvenience. Now you can avoid these problems and obtain a sample every time as only a blood sample needs to be collected. Conveniently, you can collect this at the same time as blood is taken for other renal function tests.


ClinicianEfficiency gains in the clinic:

Efficiency gains in the laboratory:

Initial Investigation Protocol

Evidence for the Investigation Protocol

Clinical Evidence for the Utility of Freelite

Serum Free Light Chain Information PackSerum Free Light Chain Information Pack

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References

  1. Jerry A. Katzmann, Angela Dispenzieri, Robert A. Kyle, Melissa R. Snyder, Matthew F. Plevak, Dirk R. Larson, Roshini S. Abraham, John A. Lust, L. Joseph Melton III, and S. Vincent Rajkumar.
    "Elimination of the Need for Urine Studies in the Screening Algorithm for Monoclonal Gammopathies by Using Serum Immunofixation and Free Light Chain Assays"
    Mayo Clin Proc. 2006;81(12):1575-1578

    Reference: MKG343 Quantity:

  2. Peter G. Hill, Julia M. Forsyth, Baldeep Rai, and Stewart Mayne
    "Serum Free Light Chains: An Alternative Test to Urine Bence Jones Proteins When Screening for Monoclonal Gammopathies"
    Clin Chem 2006 52: 1743-1748.

    Reference: MKG326 Quantity:

  3. A.R. Bradwell, G.P. Mead, H.D. Carr-Smith
    Serum Free Light Chain Analysis
    4th edition paperback

    The book is available to order US $75. More Information

    Reference: MKG290 Quantity: