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01 December 2008

New paper suggests sFLC assays aid assessment of acute renal failure

Myeloma KidneyA recent BMC Nephrology on-line article concluded:

"The measurement of serum FLCs [free light chains] can be a practical and highly sensitive aid in the identification of myeloma as the underlying pathology in patients with severe renal failure. Using an extended renal failure reference range for the FLC ratio increased the specificity of the assays. The diagnostic accuracy of these assays and their rapid laboratory turn-around time should aid nephrologists in their assessment of acute renal failure."

Serum free light chain measurement aids the diagnosis of myeloma in patients with severe renal failure.
Colin A Hutchison et al. BMC Nephrology 2008;9:11 doi: 10.1186/1471-2369-9-11

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